Job Description

Research Scientist
Job Number: 21-04850
Be part of a company that delivers life-changing healthcare solutions. Eclaro is looking for a Research Scientist for our client in San Diego, CA
Eclaro’s client is a leader in the Biopharmaceutical Industry, providing quality, innovative, and affordable medicines that make a difference in the lives of patients all over the world. If you’re up to the challenge, then take a chance at this rewarding opportunity!
  • Will work collaboratively in a multi-disciplinary environment to:
    • Explore disease biology enabling identification of Client drug targets
    • Develop and implement robust cellular assays to support discovery of small molecules as clinical development candidates
    • Design and execute research strategies that further our understanding of the mechanisms of Client compounds and targets
    • Develop collaboration and interact with external partners relevant to the target discovery efforts
  • Responsibilities include utilizing disease models to design target validation studies and relevant assays in support of SAR, mechanism of action, mechanisms of resistance, biomarker selection, and disease positioning
  • Will work within discovery project teams and with scientists across different functional areas and be expected to present her or his work at project team meetings and to research leadership
  • Work independently to design, execute, analyze, interpret and troubleshoot scientific experiments in molecular and cell biology, cellular biochemistry and assay development
  • Contribute to computational analyses that leverage internal, public and partner datasets and empower data-driven decisions for new target prioritization and validation
  • Accurately maintain written reports and present results in an organized and timely manner to research leadership
  • Communicate effectively with peers and supervisors, foster teamwork and contribute to collaborative efforts
  • Strong commitment to quality and demonstrate adaptability
  • Extensive experience designing, implementing and analyzing compound effect using multiple platforms (multi-parameter flow cytometry, Incucyte, Western blot, ELISA/MSD, and functional assays such as cytotoxicity, cell cycle and apoptosis) in the context of drug discovery
  • Hands-on experience in mammalian cell culture using primary, single and/or co-culture cell models, including genetic manipulation techniques such as CRISPR RNP nucleofection and/or lentiviral transduction
  • Flexibility and interest in learning new techniques and skills in accordance with the research program needs
  • Proficiency in scientific and data analysis programs including FlowJo, Microsoft Excel, PowerPoint, GraphPad Prism
  • Ability to work in a fast-paced dynamic team environment; flexibility to adapt to changes with a positive attitude and independently collaborate across teams, requiring excellent communication skills, both written and verbal, with strong interpersonal skills
  • Ph.D. level in cell biology, immunology, molecular biology or equivalent field with 0-3 years of experience, or M.S. degree with a minimum of 4-6 years of experience or BSc with a minimum of 6-8 years of experience in biopharmaceutical industry developing and optimizing cell-based assays
Preferred Qualifications:
  • Experience working on lymphoma and/or myeloma tumor biology
  • Experience of computational biology research on a wide variety of molecular profiling platforms, including mRNA profiling, mutational profiling, DNA copy number quantification, epigenetic profiling and proteomics
If hired, you will enjoy the following Eclaro Benefits:
  • 401k Retirement Savings Plan administered by Merrill Lynch
  • Commuter Check Pretax Commuter Benefits
  • Eligibility to purchase Medical, Dental & Vision Insurance through Eclaro
If interested, you may contact:
June Binuya
June Binuya | LinkedIn
Equal Opportunity Employer: Eclaro values diversity and does not discriminate based on Race, Color, Religion, Sex, Sexual Orientation, Gender Identity, National Origin, Age, Genetic Information, Disability, Protected Veteran Status, or any other legally protected group status

Application Instructions

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