Job Description

Postdoctoral Scientist
Job Number: 21-03010
Be part of a company that delivers life-changing healthcare solutions. Eclaro is looking for a Postdoctoral Scientist for our client in New Brunswick, NJ.
Eclaro’s client is a leader in the Biopharmaceutical Industry, providing quality, innovative, and affordable medicines that make a difference in the lives of patients all over the world. If you’re up to the challenge, then take a chance at this rewarding opportunity!

Position Overview:
  • A Post-Doctoral Fellow specializing in Computational Biology/Biophysics.
  • Will develop and implement new approaches for assessing the developability of therapeutic proteins using formulation data and molecular-level insights from modeling.
  • Will also be responsible for interfacing with portfolio or matrix teams to identify and prioritize problems that can be addressed with molecular modeling and will then implement those approaches and disseminate relevant insights back to the teams.
  • Use static, software-driven atomistic modeling approaches to assess antibody liabilities based on sequence and structure.
  • Develop and/or implement Client molecular modeling approaches to understand the role of excipients in protein drug product formulations and their impact on typical liabilities such as aggregation, viscosity, opalescence and oxidation.
  • Collaborate with experimental colleagues to identify and prioritize key business needs.
  • Automate established molecular modeling workflows and integrate them with cloud computing resources.
  • Drive the publication of modeling results and present at external conferences.
  • Ph.D. in Computational Biology, Biophysics, Chemistry or other science or engineering field with a focus on Molecular Dynamics simulations of protein systems.
  • Working knowledge of Molecular Dynamics software such as NAMD, Gromacs, Amber, LAMMPS or OpenMM.
  • Experience with MOE or Schrodinger also preferred.
  • Extensive coding experience in Python, R, Java, C++ or Fortran required.
  • Comprehensive knowledge and understanding of protein folding and structure-activity relationship, protein/peptide chemistry, chemical and physical stability.
  • Knowledge of standard biophysical and biochemical analytical tools used for protein characterization and development is preferred.
  • Excellent interpersonal, collaborative, team-building, and communication skills.
  • Strong written and verbal presentation skills; able to distill complex topics and present effectively to cross-functional teams.
If hired, you will enjoy the following Eclaro Benefits:
  • 401k Retirement Savings Plan administered by Merrill Lynch
  • Commuter Check Pretax Commuter Benefits
  • Eligibility to purchase Medical, Dental & Vision Insurance through Eclaro
If interested, you may contact:
Jane Bautista
Jane Bautista | LinkedIn

Equal Opportunity Employer: Eclaro values diversity and does not discriminate based on Race, Color, Religion, Sex, Sexual Orientation, Gender Identity, National Origin, Age, Genetic Information, Disability, Protected Veteran Status, or any other legally protected group status.

Application Instructions

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