Job Description

CEL - Research Associate
JobDiva # 21-01851

Be part of a company that delivers life-changing healthcare solutions. Eclaro is looking for a CEL - Research Associate for our client in Seattle, WA.  

Eclaro’s client is a leader in the Biopharmaceutical Industry, providing quality, innovative, and affordable medicines that make a difference in the lives of patients all over the world. If you’re up to the challenge, then take a chance at this rewarding opportunity!

Position Overview:
  • Juno Therapeutics (a Client company) is a global biopharmaceutical company leading the way in medical innovation to help patients live longer, better lives. Our purpose as a company is to Client and develop therapies that will change the course of human health. We value our passion for patients, quest for innovation, spirit of independence and love of challenge. With a presence in more than 70 countries, and growing we look for talented people to grow our business, advance our science and contribute to our unique culture.
  • The Research Associate will join our viral vector process development group supporting process development, production and characterization of viral vectors, which are key intermediates in the CAR-T drug product. The candidate will run cell-based assays using Jurkat cells as a surrogate method to vector infectivity. Additionally, this candidate will provide process development support to current programs and advance our capabilities in vector production.

Responsibilities:
  • Hands-on experimental work in running a Jurkat cell-based assay.
  • Method includes culturing cells, staining, and flow cytometry for quantification
  • Hands-on experimental work in the development and optimization of upstream (cell culture and transfection conditions) and downstream (clarification, tangential flow filtration, chromatography) unit operations for viral vector production
  • Support the process development program for next-generation viral vector manufacturing platforms
  • Assist in the planning and design of experiments, execution and independent analysis of data
  • Summarize and present scientific data, communicate progress to project teams
  • Maintain proper documentation of experimental results.
  • Support process transfer, development and manufacturing at external CMOs

Qualifications:
  • B.S. in Engineering, Virology, Biology, Biochemistry, or related discipline
  • 0-2 years of industry experience in process development
  • Independently motivated with the ability to multi-task, troubleshoot, problem-solve, and work in teams
  • Ability to communicate clearly and concisely through oral presentation and technical writing

Preferred Skills:
  • Experience in mammalian cell culture, transfection, harvest and purification of biological products
  • Experience in downstream process development using equipment such as the AKTA Avant
  • Working knowledge of chromatography, UF/DF, and normal flow filtration operations
  • Hands-on purification experience with lentivirus and ability to cross train and support upstream operations
  • Experience with general analytical protocols (e.g. ELISA, qPCR, flow cytometry, etc.) and ability to operate associated analytical equipment and interpret results
  • Process transfer and cGMP manufacturing experience

If hired, you will enjoy the following Eclaro Benefits:
  • 401k Retirement Savings Plan administered by Merrill Lynch
  • Commuter Check Pretax Commuter Benefits
  • Eligibility to purchase Medical, Dental & Vision Insurance through Eclaro

If interested, you may contact:
 
Jay Lucas
arjay.lucas@eclaro.com
6463571240
Jay Lucas | LinkedIn

Equal Opportunity Employer: Eclaro values diversity and does not discriminate based on Race, Color, Religion, Sex, Sexual Orientation, Gender Identity, National Origin, Age, Genetic Information, Disability, Protected Veteran Status, or any other legally protected group status.

Application Instructions

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