Job Description

Biologics Development Associate

Job Number: 21-09036

 

Be part of a company that delivers life-changing healthcare solutions. Eclaro is looking for a Biologics Development Associate for our client in New Brunswick, NJ.

 

Eclaro’s client is a leader in the Biopharmaceutical Industry, providing quality, innovative, and affordable medicines that make a difference in the lives of patients all over the world. If you’re up to the challenge, then take a chance at this rewarding opportunity!

 

Position Overview:

  • In stem cell biology, differentiation and dedifferentiation are governed by transcriptional changes as well as by epigentic changes.
  • Recent publications show, that certain epigenetic changes during single cell cloning in CHO cells are correlated with improved titers in clones, suggesting that these changes are inherited during cell division, and therefore stable.
  • The dedifferentiation state, such as it happens in the induced pluripotent stem cells, can be achieved and maintained by small molecules supplemented in medium.
  • Here, we propose to compile a comprehensive literature search to identify factors and/or small molecules that lead to epigenetic changes.
  • Identified candidate molecules can then be supplemented into cloning medium during single cell cloning of transfected CHO cells.
  • The aim will be to test the impact of these factors and small molecules in enhancing the specific productivity of monoclonal antibodies in CHO production cells.
  • Business Justification for the Project
  • Enhancing the specific productivity of production CHO cell lines.
  • Literature search, Reprogramming, Stem Cells, iPCs, Cell Differentiation, Cell culture, aseptic technique, media supplementation, cloning media
  • Provide additional details about how you will engage and support the student to build their interest in both Biopharma careers and Client as pre-eminent employer in this field.
  • This project will introduce the intern to a variety of technical and scientific areas of cell line development including clone selection.
  • The intern will regularly interact with the mentor and sponsor to learn new techniques and obtain a general overview of pharmaceutical process development.
  • This will continue to foster a good relationship between academic programs and Client while introducing students to projects that improve business timelines in addition to enhancing scientific innovation.

 

If hired, you will enjoy the following Eclaro Benefits:

  • 401k Retirement Savings Plan administered by Merrill Lynch
  • Commuter Check Pretax Commuter Benefits
  • Eligibility to purchase Medical, Dental & Vision Insurance through Eclaro

 

If interested, you may contact:

Jay Lucas

arjay.lucas@eclaro.com

6463571240

Jay Lucas | LinkedIn

 

Equal Opportunity Employer: Eclaro values diversity and does not discriminate based on Race, Color, Religion, Sex, Sexual Orientation, Gender Identity, National Origin, Age, Genetic Information, Disability, Protected Veteran Status, or any other legally protected group status.

Application Instructions

Please click on the link below to apply for this position. A new window will open and direct you to apply at our corporate careers page. We look forward to hearing from you!

Apply Online